This seems to really vary from system to system, so there's no way you can tell until you try it.
You should probably try disabling sound acceleration first, with the anti-skip patch turned off (you toggle this in Standoff's launcher options screen), since it's the fix that seems to be more reliable. However, it might not work for you (or you might just not want to turn your sound acceleration off, since it might get in the way of other games or whatever).
In that case, you should try turning sound acceleration back on and enabling the anti-skip patch instead. This is the only way to fix the movies in some systems, but it's been reported that it can cause comms to stutter when your framerate is low during missions.