No, not yet. But You give me the reason to try. I will report!Hmmm.... have you tried playing SO1 on a standard DOSBox build to test if the missile button works in that enviroment?
Btw those YKHWong builds are fantastic, especially because of Munt Reloaded. I use them myself but I haven tried WC2 on that build yet.
dont know if this will help but, I play the GOG version and I noticed if there are too many enemies on the screen missiles will not fire, after you clear a couple out thing return to normal with the missiles.